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Sildenafil boosts the impact of NO by inhibiting phosphodiesterase kind five (PDE5), and that is to blame for degradation of cGMP while in the corpus cavernosum. Sildenafil has no direct relaxant impact on isolated human corpus cavernosum.Dette kan spesielt være dersom tabletten tas med et stort eller fett måltid kan absorberingen av virkemiddele

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